Nico Paz scored in the second minute, and Douvikas, Paz and Jacobo Ramon also found the net for Como, with Zirkzee's late goal for United.
Matthijs de Ligt started for Manchester United for the first time since November of last year, after a long back injury.
Como scored four goals against a Manchester United side that struggled throughout. Nico Paz opened the scoring in the second minute, after Harry Maguire gave him too much room, and he doubled the lead soon after the break by setting up Anastasios Douvikas. Paz added a third after taking the ball from substitute Carlos Baleba, and Jacobo Ramon headed in a fourth with a quarter of an hour left. Joshua Zirkzee, who came on as a substitute, scored a late goal for United.
For Matthijs de Ligt, the 27-year-old centre-back, the match marked a return to action after a long layoff with a persistent back problem. He had not touched the ball before United fell behind. Como, a Champions League debutant, had lost 3-2 at Feyenoord the previous week after beating RB Leipzig 4-1. United, 13th in the Premier League, have now gone six matches without a win.
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Como won its second home Champions League match 4-1 against Manchester United. Matthijs de Ligt made his first starting appearance since a back injury that had kept him out since November of last year.
AI text based on reports by NOS. Published .