Research on Cancer in Cats Opens New Possibilities for Human Treatment

Scientists from prestigious institutions, including the Wellcome Sanger Institute and the University of Bern, have made a breakthrough discovery in the field of comparative oncogenomics. They analyzed tumor samples from domestic cats, creating the first such detailed genetic map of feline cancers. The publication results indicate that the DNA changes in cats suffering from cancer are almost identical to those observed in human oncology patients. This is particularly true for breast cancer, where the molecular mechanisms in both species show a remarkable convergence. Cats, like dogs, share the same environment as humans and are exposed to the same stressors and pollutants that can induce cancer formation. However, until now, research on feline oncology has been far less advanced than for dogs. The new genetic map fills this gap, allowing for the identification of specific mutations responsible for disease progression. Experts advocate for closer collaboration between doctors and veterinarians within the "One Health" concept. Research on cancer in animals as a model for human diseases dates back to the 20th century, but only the development of next-generation DNA sequencing technology in the early 21st century has enabled such precise cross-species comparisons. By identifying common therapeutic targets, it will become possible to test innovative drugs that will be effective in both species. As the study authors note, cats develop cancer spontaneously, making them a much better research model than artificially modified laboratory mice. This discovery could accelerate work on personalized medicine, where drug selection is based on the genetic profile of a specific tumor. „Researchers analyzed genetic changes that could help treat conditions in both humans and animals.” — Paulina Mozolewska 25% — of British households own at least one cat Integrating data from veterinary oncology and human medicine could revolutionize the approach to aggressive cancers. Scientists hope that further research will allow for the creation of a catalog of drugs with dual applications. This is particularly important in light of the growing number of cancer cases among pets, which is becoming a challenge for modern veterinary medicine.